Our start-up portfolio

We've built an incredible production line for start-up companies to bring early-stage technologies out of the research lab and translate them into patient benefit. Our start-up portfolio secures funding from investors around the world who believe in our world class science and the power of partnership.

Three women speaking together

95+

start-ups formed across therapeutics, diagnostics and medtech

24

start-up exits to date

£3.55bn+

raised by our start-up portfolio

Simon Boulton talking about his company ALTx at the Cancer Research Horizons Investor Networking Breakfast in November 2025

ALTx Therapeutics launches with £12.55m of funding

Portfolio news

Based on the pioneering work of British scientist Simon Boulton, ALTx leverages fundamental insights in cancer cell immortalisation to develop novel treatments for cancer. Spinning out of The Francis Crick Institute, ALTx will be advanced by the Slingshot accelerator in collaboration with the Crick with funding from Syncona, the Crick and our Seed Fund.

Read more

Active start-ups

Professor Steve Pollard in his lab

How Steve Pollard created the Trojan horse of cancer treatments

A founder's perspective

I was very lucky that Cancer Research UK supported me with a project grant, realising that these are good model systems.
Steve Pollard, CSO and founder of Trogenix

Steve Pollard’s research into transcription factors driving brain development has been quite the ride. Now advances in viral gene delivery – and a £70m Series A, including Cancer Research Horizons' largest ever investment – have sent a highly targeted glioblastoma immunotherapy heading toward the clinic.

Learn more

Exited start-ups

Logo of Abcodia - detecting cancer earlier

Abcodia

Adaptate logo

Adaptate Biotherapeutics

Autolus logo

Autolus

Curis logo

Curis

Cyclacel logo

Cyclacel

Epistem logo

Epistem

Gamma Delta logo

GammaDelta Therapeutics

Genextra logo

Genextra

Infermed logo

Infermed

Inivata logo

Inivata

Kudos pharmaceuticals logo

KuDOS Pharmaceuticals

Logo of Monte Rosa Therapeutics

Monte Rosa Therapeutics

The Native Antigen Company logo

The Native Antigen Company

Photo Therapeutics

Photo Therapeutics

Piramed

Piramed

Sorrento therapeutics Logo

Sorrento Therapeutics

Spirogen logo

Spirogen

Let's go further, faster, together

Find out how to invest in one of our portfolio companies or get support to start your own.

Contact the Ventures team